I have found backmarkers from inside alleys [except perhaps barrier 1 or 2 say] more or less have to go forward with the pace for general field safety reasons and require a good senior jockey [and a bit of luck] usually, to get into a winning position from anywhere except outside alleys.

From the outside alleys, far less experience is required and overall outside barrier lanes suit Backmarkers as much as inside lanes suit leaders. Safety is always a big thing and most jockeys drawn badly on backmarkers will be there for the scenery as they like to go home at night. If it's a big race [$$$] they might take a few worthwhile risks.

Sole leaders require riders with a good judge of pace [senior Jockey in most cases] or they will burn out before the post with poor pace judgment. Inside barriers are best but it's not that hard for a lone leader with a good jockey to cross early from the outside lanes as long as they get a clean jump away [stuffed otherwise]. 1100m + distances for obvious reasons, recommended in those situations though.