Chicka,

Trend Micro and Spyware Doctor are both excellent, but nothing does it all.

Try this though, download Spyware Blaster from Javacool: http://www.javacoolsoftware.com/spywareblaster.html and enable it's defences [it stops spyware BEFORE it gets onto your PC]. Since I added that one to my arsenal, my spybot and ad-aware rarely find anything to delete. The odd tracking cookie is found by ad-ware but spybot has found nothing and I rarely run it's 'check for problems' now.

Javacool's SywareBlaster Blurb:
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'Spyware, adware, browser hijackers, and dialers are some of the fastest-growing threats on the Internet today.
By simply browsing to a web page, you could find your computer to be the brand-new host of one of these unwanted fiends!

The most important step you can take is to secure your system. And SpywareBlaster is the most powerful protection program available.

Prevent the installation of ActiveX-based spyware, adware, browser hijackers, dialers, and other potentially unwanted software.
Block spyware/tracking cookies in Internet Explorer and Mozilla/Firefox.
Restrict the actions of potentially unwanted sites in Internet Explorer.

SpywareBlaster can help keep your system spyware-free and secure, without interfering with the "good side" of the web.

And unlike other programs, SpywareBlaster does not have to remain running in the background.

SpywareBlaster is freeware for personal and educational use'.
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..and if you want to get the best browser around that leaves all others for dead, check out 'Avant' : http://www.avantbrowser.com/
Fully IE compatible too. If you do try it [and you'll never look back if you do] just make sure you untick the 'google toolbar' option first if it has one [I can't remember], as that thing has security issues that are still unfixed.

Cheers.